Topic 1: Discuss how you used the three components inherent to Evidence-Based Practice inquiry to direct your clinical question database search.

My PICOT question, “In psychiatric patients diagnosed with Major Depressive Disorder (MDD) how quick is observed the onset of antidepressant effects of selective N-Methyl-D-Asparate (NMDA) receptor antagonists in comparison with the onset of antidepressant effects of selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) during the first week of treatment?”

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