Part1

1. Which structural features are in common to all viruses, and which are not? Complete the table below to answer the questions based upon the information provided in the case.

2. Why are viruses considered parasites?

3. Examine the diagram of the viral particle below. Label all of the important structures on the virus that you identified in the table above.

4. Design a. Imaginary viral particle. Create a diagram of your virus and label its major features. Your virus should have different capsid shape( eg. icosahedral, helical, complex) than the one above and be non-enveloped.

Part 2

1. Why is viral attachment to the host cell specific between one virus and one type of cell?

2. List several types of host cells and the associated virus that binds to the host cell .

3. What are three major ways in which a virus enters a host cell to deliver its genome?

4. Formulate a hypothesis as to why there is more than one mechanism of viral entry into host cells.

Part3

1. Describe the essential cell ‘ machinery ‘ that viruses use to make new virus.

2. Why do viruses need the machinery to make more viruses? Why can’t they replicate on their own?

3. What are the structures that need to put together during viral assembly? Consider the key structural components of viruses described earlier.

4. How does the army of new viruses get out of cell to infect the nearby cells?

5. Examine the diagram below depicting viral infection of a typical cell.

A. Identify all (five) of the steps used by viruses to get into the cell, make copies of viral protein and leave the cell as an army of viruses out to attack nearby cells.

B. Label the two cellular components indicated in the diagram.

Part4

1. Examine the diagram showing the life cycle of the Ebola virus.

A. Label the five major steps used by Ebola virus to infect cells. In what specific ways are these similar or different from those you labeled in the general virus life cycle?

B. Label the key viral and cellular factors in the indicated area of the diagram. Describe each of their roles.

2. Formulate a hypothesis as to what would happen to viral replication and budding from the cell if the ribosomes did not make VP40?

3. What is one structural component of the Ebola virus to target for a vaccine that prevents infections like Terry’s. Explain your answer . Keep in mind the Ebola virus structures and vaccines are developed to prevent viral infections (for example, the flu vaccine contains a weakened form of the influenza virus that does not cause the disease).

Label the viral factors

Label The cellular factors

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